455264-47-8Relevant academic research and scientific papers
Catalytic enantioselective desymmetrization of cyclobutane-1,3diones by carbonyl-amine condensation
Wen, Kai-Ge,Liu, Chao,Wei, Dong-Hui,Niu, Yan-Fei,Peng, Yi-Yuan,Zeng, Xing-Ping
supporting information, p. 1118 - 1122 (2021/02/16)
A chiral phosphoric acid-catalyzed enantioselective condensation of 2,2-disubstituted cyclobutane-1,3-diones with a primary amine is described. This reaction offered a mild and efficient protocol for constructing quaternary carbon-containing cyclobutanes
Efficient synthesis of 3-aminocyclobut-2-en-1-ones: Squaramide surrogates as potent VLA-4 antagonists
Brand, Stephen,De Candole, Benjamin C.,Brown, Julien A.
, p. 2343 - 2346 (2007/10/03)
(Matrix presented) A novel series of uniquely functionalized 3-aminocyclobut-2-en-1-ones has been prepared by facile condensation of a variety of cyclobuta-1,3-diones with a phenylalanine-derived primary amine. These systems subsequently lend themselves t
