455310-87-9Relevant academic research and scientific papers
Palladium(II)-catalyzed conjugate phosphination of electron-deficient acceptors
Trepohl, Verena T.,Mori, Susumu,Itami, Kenichiro,Oestreich, Martin
supporting information; experimental part, p. 1091 - 1094 (2009/07/25)
A general protocol for the conjugate transfer of diphenyl-, dicyclohexyl-, and di-tert-butylphosphinyl groups from silylphosphines to cyclic and acyclic electron-deficient acceptors employing a bench-stable palladium(II) catalyst is reported. Several Eand
Conjugate phosphination of cyclic and acyclic acceptors using Rh(I)-phosphine or Rh(I)-carbene complexes. Probing the mechanism with chirality at the silicon atom or the phosphorus atom of the Si-P reagent
Trepohl, Verena T.,Fr?hlich, Roland,Oestreich, Martin
scheme or table, p. 6510 - 6518 (2011/02/26)
The Rh(I)-catalyzed conjugate phosphinyl transfer from an Si-P reagent to an electron-deficient acceptor requires individual protocols for cyclic and acyclic α,β-unsaturated carbonyls and carboxyls. While 1,4-addition to cyclic acceptors is catalyzed by a
Rhodium(I)-catalysed conjugate phosphination of cyclic α,β- unsaturated ketones with silylphosphines as masked phosphinides
Trepohl, Verena T.,Oestreich, Martin
, p. 3300 - 3302 (2008/02/13)
Nucleophile-activation of the phosphorus(iii)-silicon linkage in silylphosphines generates a nucleophilic phosphorus(iii) equivalent thereby allowing for a rhodium-catalysed conjugate phosphination of β-substituted α,β-unsaturated acceptors. The Royal Soc
P-C Bond formation via direct and three-component conjugate addition catalyzed by 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD)
Jiang, Zhiyong,Zhang, Yan,Ye, Weiping,Tan, Choon-Hong
, p. 51 - 54 (2007/10/03)
The direct addition of P(O)-H bonds (dialkyl phosphites and diphenyl phosphonite) across various activated alkenes was catalyzed effectively by 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD). This is a mild, rapid and efficient protocol to generate P-C bonds.
Towards chiral non-racemic cis-1,3-disubstituted cyclopentane 1,4-diphosphines
Camps, Pelayo,Colet, Gisela,Font-Bardia, Merce,Muoz-Torrero, Victoria,Solans, Xavier,Vazquez, Santiago
, p. 759 - 778 (2007/10/03)
Reaction of dialkyl- or diaryl-trans-(3,4-epoxycyclopentyl)phosphine oxides 2 with the lithium derivative of methyldiphenylphosphine oxide gives a mixture of (±)-t-4- and (±)-c-4-(disubstituted phosphinoyl)-t-2-(diphenylphosphinoylmethyl)-r-1-cyclopentanol derivatives 13a-c and 16a-c, which could be obtained in pure form by separation of the corresponding acetates 14a-c and 17a-c followed by methanolysis. Compounds 13b and 16b were transformed into the corresponding dehydroxy derivatives 19 and 21 through the Barton procedure. Additionally, 16a was transformed into a diastereomeric mixture of carbamates 22 and 23 on reaction with (S)-α-phenylethylisocyanate which could be separated by repeated crystallization. The relative configuration of compounds 13b, 17a, 21 and 22 was established by X-ray diffraction analysis.
