455331-73-4Relevant academic research and scientific papers
Total synthesis of yahazunol, zonarone and isozonarone
Laube, Thorsten,Schr?der, J?rg,Stehle, Ralf,Seifert, Karlheinz
, p. 4299 - 4309 (2002)
The synthesis of the marine natural products zonarone and isozonarone was achieved via (+)-albicanic acid, a sesquiterpene of the drimane type. Coupling of the appropiate drimane-synthon with lithiated hydroquinone ethers led to sesquiterpene arenes, which were further modified to the target molecules. Stereoselective epoxidation followed by regioselective opening of the oxirane ring yielded yahazunol.
