455934-76-6

Upstream product

• 105729-41-7 3-(R)-t-butyldimethylsilyloxybutanoic acid 
• 294198-50-8 2,2,2-trichloroethyl (4R,5S)-4-benzyloxy-5-hydroxy-2(E)-hexenoate 

Downstream Products

• 455934-67-5 (E)-(4R,5S)-4-Benzyloxy-5-{(R)-3-[(E)-(S)-5-(tert-butyl-dimethyl-silanyloxy)-hex-2-enoyloxy]-butyryloxy}-hex-2-enoic acid 2,2,2-trichloro-ethyl ester 
• 455934-68-6 (E)-(4R,5S)-4-Benzyloxy-5-[(R)-3-((E)-(S)-5-hydroxy-hex-2-enoyloxy)-butyryloxy]-hex-2-enoic acid 2,2,2-trichloro-ethyl ester 
• 455934-69-7 (E)-(4R,5S)-4-Benzyloxy-5-[(R)-3-((E)-(S)-5-hydroxy-hex-2-enoyloxy)-butyryloxy]-hex-2-enoic acid 
• 455934-70-0 (7E,13E)-(4R,10S,15R,16S)-15-Benzyloxy-4,10,16-trimethyl-1,5,11-trioxa-cyclohexadeca-7,13-diene-2,6,12-trione 
• 455934-66-4 (E)-(4R,5S)-4-Benzyloxy-5-((R)-3-hydroxy-butyryloxy)-hex-2-enoic acid 2,2,2-trichloro-ethyl ester 

Relevant academic research and scientific papers

New total syntheses of (+)-macrosphelides C, F and G

The total synthesis of (+)-macrosphelide C 1 (25% overall yield in nine steps), (+)-macrosphelide F 2 (20% overall yield in nine steps) and (+)-macrosphelide G 3 (22% overall yield in nine steps) has been achieved from the chemoenzymatic reaction product