456-43-9

Basic information

• Product Name: 4-Bromo-2-fluoromethylbenzene
• Synonyms: 4-Bromo-2-fluoromethylbenzene
• CAS NO: 456-43-9
• Molecular Formula: C7H6BrF
• Molecular Weight: 189.027
• Mol File: 456-43-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-Bromo-2-fluoromethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-2-fluoromethylbenzene(456-43-9)
• EPA Substance Registry System: 4-Bromo-2-fluoromethylbenzene(456-43-9)

Safety Data

• Hazardous Substances Data: 456-43-9(Hazardous Substances Data)

Upstream product

• 15852-73-0 (3-Bromophenyl)methanol 
• 82732-02-3 3-bromobenzyl methanesulfonate 
• 823-78-9 meta-bromobenzyl bromide 

Downstream Products

• 20600-29-7 1-bromo-3-(phenoxymethyl)benzene 
• 96258-62-7 1-formyl-3-(fluoromethyl)benzene 
• 82732-04-5 2-<3-(fluoromethyl)phenyl>-2-propanol 
• 3132-99-8 m-bromobenzoic aldehyde 
• 1360860-57-6 C₁₂H₁₀FNO 
• 82732-05-6 2-<3-fluoromethyl)phenyl>-2-propyl chloride 
• 96258-48-9 Methanesulfonic acid (diethoxy-phosphoryl)-(3-fluoromethyl-phenyl)-methyl ester 
• 96258-67-2 [(3-Fluoromethyl-phenyl)-trimethylsilanyloxy-methyl]-phosphonic acid diethyl ester 
• 96258-73-0 [(3-Fluoromethyl-phenyl)-hydroxy-methyl]-phosphonic acid diethyl ester 
• 82732-03-4 1,1'-(1,2-ethanediyl)bis-3-bromobenzene 
• 856191-91-8 (3-bromo-phenyl)-p-tolyl-methane 

Relevant articles and documents

9-Borabicyclo[3.3.l]nonane-induced Friedel-Crafts benzylation of arenes with benzyl fluorides

Friedel-Crafts benzylation of arenes with benzyl fluorides using 9-borabicyclo[3.3.l]nonane (9-BBN) as a mediator has been developed. This provides a simple and cheap route to the activation of C-F bonds to synthesize 1,1-diarylmethanes in good to excellent yields (up to 98%) under mild conditions. Functional group tolerance and the mechanism are considered.

FLUORINATION OF HALOGENO ALCOHOLS WITH 1,1,2,3,3,3-HEXAFLUOROPROPYL DIETHYLAMINE

Fluorination of halogeno alcohols with 1,1,2,3,3,3-hexafluoropropyl diethylamine (PPDA) was investigated. 2-Bromo-1-fluorobutane was obtained from the reaction of PPDA and 2-bromo-1-butanol (yield 50percent).Similar results were obtained from other alipha