4564-87-8 Usage
Description
Carbomycin is a sixteen-membered-ring macrolide antibiotic complex, similar to Leucomycin and Erythromycin, which is produced by Streptomyces halstedii. It is known for its potent antibacterial properties and has been widely used in the medical field.
Uses
Used in Pharmaceutical Industry:
Carbomycin is used as an antibiotic for treating a variety of bacterial infections. Its broad-spectrum activity makes it effective against both gram-positive and gram-negative bacteria, including Streptococcus, Staphylococcus, and Haemophilus species. It works by inhibiting bacterial protein synthesis, thus stopping the growth and reproduction of the bacteria.
Additionally, carbomycin can be used in combination with other antibiotics to enhance their effectiveness and combat antibiotic-resistant strains. This makes it a valuable asset in the development of new antimicrobial therapies and the fight against drug-resistant infections.
Originator
Magnamycin,Pfizer,US,1953
Manufacturing Process
A selected strain of Streptomyces halstedii was cultivated in an aqueous
nutrient medium under aerobic conditions and the resulting broth containing
carbomycin antibiotics was filtered. The solutions was extracted twice at pH
6.5 with one-quarter volume of methyl isobutyl ketone. The combined extracts
were concentrated to one-tenth volume under vacuum, and the antibiotics
were extracted into water adjusted to a pH of about 2 with sulfuric acid. After
adjusting the separated aqueous solution to pH 6.5, the antibiotic was
extracted into benzene and the solution was concentrated to a small volume.
Addition of hexane resulted in the separation of a solid product containing the
benzene complexes of carbomycin A and carbomycin B, present in the
fermentation broth.
Therapeutic Function
Antibiotic
Safety Profile
Poison by
subcutaneous route. Moderately toxic by
intravenous and intramuscular routes. When
heated to decomposition it emits toxic
fumes of NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 4564-87-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,6 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4564-87:
(6*4)+(5*5)+(4*6)+(3*4)+(2*8)+(1*7)=108
108 % 10 = 8
So 4564-87-8 is a valid CAS Registry Number.
InChI:InChI=1/C42H67NO16/c1-21(2)16-32(47)57-40-25(6)53-34(20-42(40,8)50)58-37-24(5)54-41(36(49)35(37)43(9)10)59-38-27(14-15-44)17-22(3)28(46)12-13-29-30(56-29)18-23(4)52-33(48)19-31(39(38)51-11)55-26(7)45/h12-13,15,21-25,27,29-31,34-41,49-50H,14,16-20H2,1-11H3/b13-12+/t22-,23-,24?,25?,27+,29?,30+,31-,34?,35?,36?,37?,38+,39+,40?,41?,42?/m1/s1