45680-22-6

Upstream product

• 109-72-8 n-butyllithium 
• 98-81-7 1-bromovinylbenzene 

Downstream Products

• 119908-13-3 3-ethoxy-4-hydroxy-2-phenyl-4-(1-phenylethenyl)-2-cyclobuten-1-one 
• 83196-14-9 {[(1R,2R)-2-Hydroxy-2-(1-phenyl-vinyl)-cyclohexyl]-methyl-amino}-acetonitrile 
• 83196-04-7 (1S,2R)-2-(Benzhydryl-amino)-1-(1-phenyl-vinyl)-cyclohexanol 
• 83196-04-7 (1R,2R)-2-(Benzhydryl-amino)-1-(1-phenyl-vinyl)-cyclohexanol 
• 114550-56-0 (3S,4S)-4-((ethoxycarbonyl)amino)-2,3-diphenyl-1-penten-3-ol 
• 96617-24-2 {[(1S,2S)-2-Hydroxy-2-(1-phenyl-vinyl)-cyclobutyl]-methyl-amino}-acetonitrile 
• 96617-28-6 2-{[(1S,2S)-2-Hydroxy-2-(1-phenyl-vinyl)-cyclobutyl]-methyl-amino}-propionitrile 
• 96617-23-1 {Benzyl-[(1S,2S)-2-hydroxy-2-(1-phenyl-vinyl)-cyclobutyl]-amino}-acetonitrile 
• 96617-27-5 2-{Benzyl-[(1S,2S)-2-hydroxy-2-(1-phenyl-vinyl)-cyclobutyl]-amino}-propionitrile 
• 79076-06-5 cis-2-(methylamino)-1-(1-phenylethenyl)cyclopentanol 
• 882-33-7 diphenyldisulfane 
• 63935-90-0 1-(dimethyl(phenyl)silyl)-1-phenylethene 
• 158673-94-0 (4S,5S)-5-(4-Methoxy-benzyloxy)-2-phenyl-nona-1,8-dien-4-ol 

Relevant academic research and scientific papers

Reactions of phenylacetylene with nickel POCOP-pincer hydride complexes resulting in different outcomes from their palladium analogues

Nickel POCOP-pincer hydride complexes [2,6-(R2PO)2C6H3]NiH (R = iPr, 4a; R = cPe = cyclopentyl, 4b) react with phenylacetylene to generate [2,6-(R2PO)2C6H3]NiC(Ph)=CH2 (5a-b) as the major product and (E)-[2,6-(R2PO)2C6H3]NiCH=CHPh (6a-b) as the minor product. The 2,1-insertion is more favorable than the 1,2-insertion and both pathways involve cis addition of Ni-H across the C≡C bond. Unlike the palladium case, alkynyl complexes [2,6-(R2PO)2C6H3]NiC≡CPh (7a-b) and H2 are not produced in the nickel system. The more bulky hydride complex [2,6-(tBu2PO)2C6H3]NiH (4c) shows no reactivity towards phenylacetylene. Catalytic hydrogenation of phenylacetylene with 4a-b takes place at an elevated temperature (70-100 °C) and proves to be heterogeneous. The structures of 5b, 6a, 7a and 7b have been studied by X-ray crystallography.