457051-12-6

Basic information

• Product Name: Benzonitrile, 4-broMo-2-(broMoMethyl)-
• Synonyms: Benzonitrile, 4-broMo-2-(broMoMethyl)-;4-broMo-2-(broMoMethyl)benzonitrile
• CAS NO: 457051-12-6
• Molecular Formula: C₈H₅Br₂N
• Molecular Weight: 274.94
• Mol File: 457051-12-6.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 317.0±27.0 °C(Predicted)
• Appearance: /
• Density: 1.92±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzonitrile, 4-broMo-2-(broMoMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-broMo-2-(broMoMethyl)-(457051-12-6)
• EPA Substance Registry System: Benzonitrile, 4-broMo-2-(broMoMethyl)-(457051-12-6)

Safety Data

• Hazardous Substances Data: 457051-12-6(Hazardous Substances Data)

Upstream product

• 67832-11-5 4-bromo-2-methylbenzonitrile 

Downstream Products

• 871116-69-7 4-bromo-2-(1,2,4-triazol-1-ylmethyl)-benzonitrile 
• 864750-43-6 4-Bromo-2-(4-chloro-2-iodo-phenoxymethyl)-benzonitrile 
• 1027343-11-8 C₁₉H₂₆BrN₃O₂ 
• 1261861-86-2 4-bromo-2-(bromomethyl)benzaldehyde 
• 168759-64-6 7-bromoisochroman-4-one 
• 1075741-02-4 2-benzyl-4-bromobenzonitrile 

Relevant articles and documents

Palladium-Catalyzed Tandem Carbonylative Diels-Alder Reaction for Construction of Bridged Polycyclic Skeletons

A palladium-catalyzed tandem carbonylative lactonization and Diels-Alder cycloaddition reaction between aldehyde-tethered benzylhalides and alkenes has been developed. A range of alkenes and aldehyde-tethered benzylhalides bearing different substituents can be successfully transformed into the corresponding bridged polycyclic compounds in good yields. This strategy provides a unique approach to complex lactone-containing bridged polycyclic compounds.

INDAZOLONES AS MODULATORS OF TNF SIGNALING

The disclosure provides indazolone compounds, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are defined herein. The compounds of the disclosure may be useful for treating immunological and oncological conditions.

SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE

Compounds having a structure of Formula (IX) or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b, R3a, R3b, R4a, R4b, Q1----Q2, R6, R7, A, B, W, x, and y are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various HAT-related conditions or diseases, including cancer, by administration of such compounds are also provided.