457072-07-0

Upstream product

• 457072-36-5 N¹,N¹-dimethyl-N²-(6,7,8,9-tetrahydro-5H-cyclohepta[1,2-d]pyrimidin-4-yl)benzamidine 
• 457072-65-0 4-amino-6,7,8,9-tetrahydro-5H-cyclohepta[1,2-d]pyrimidine 
• 611-74-5 N,N-dimethylbenzamide 

Relevant academic research and scientific papers

Polycyclic N-heterocyclic compounds. Part 78: Synthesis of N-[2-([1,2,4]oxadiazol-5-yl)cyclohepten-1-yl]formamide oximes and their evaluation as inhibitors of platelet aggregation

N-[2-([1,2,4]Oxadiazol-5-yl)cyclohepten-1-yl]formamide oximes were synthesized by fusion of (6,7,8,9-tetrahydro-5H-cyclohepta[1,2-d]pyrimidin-4-yl) amidines with hydroxylamine hydrochloride through a subsequent rearrangement reaction. Effects of the products as well as the structurally related N-[4-([1,2,4]oxadiazol-5-yl)-2,3-dihydro[1]benzoxepin-5-yl]formamide oximes and N-[4-([1,2,4]oxadiazol-5-yl)-2,3-dihydro[1]benzothiepin-5-yl]formamide oximes on platelet aggregation were evaluated.