457100-59-3Relevant academic research and scientific papers
Copper(I)-Catalyzed Enantioselective 1,6-Borylation of α,β,γ,δ-Unsaturated Phosphonates
Lee, Hyesu,Yun, Jaesook
, p. 7961 - 7964 (2018)
Copper(I)-catalyzed asymmetric 1,6-borylation of 1,3-dienylphosphonates was achieved using (S,S)-Ph-BPE as a chiral ligand. Regio-, stereo-, and enantioselective borylation successfully proceeded to afford phosphonate-containing allylboronates, with high enantioselectivity up to 97% ee. Further applications of the resulting products generated a valuable phosphonate analogue of γ-butyrolactone.
The total synthesis of chlorotonil A
Rahn, Nicola,Kalesse, Markus
, p. 597 - 599 (2008/09/20)
(Chemical Equation Presented) Stacking the deck: The natural product chloronitril A contains an unprecedented motif in which a CCl2 unit in a 14-membered macrolide framework is flanked by two carbonyl groups. In the first total synthesis of chl
