457622-47-8Relevant academic research and scientific papers
Stereoselective synthesis of 3-hydroxyproline benzyl esters from N-protected β-aminoaldehydes and benzyl diazoacetate
Angle, Steven R.,Belanger, Dominique S.
, p. 4361 - 4368 (2007/10/03)
The synthesis of a series of 3-hydroxyproline benzyl esters from α-alkyl and α-alkoxy N-protected aminoaldehydes with benzyl diazoacetate is described. Aldehydes with α-alkyl substituents afforded prolines as a single diastereomer with a trans-cis relativ
N-silyl-tethered radical cyclizations: a new synthesis of gamma-amino alcohols.
Blaszykowski, Christophe,Dhimane, Anne-Lise,Fensterbank, Louis,Malacria, Max
, p. 1341 - 1344 (2007/10/03)
[reaction: see text] Various allylic and propargylic amines bearing a protecting group (PG) have been employed in N-silyl-tethered radical cyclizations. The resulting silapyrrolidine adducts could be smoothly oxidized, creating access to gamma-amino alcoh
