457654-04-5

Basic information

• Product Name: 5-(3-chlorophenyl)-3-methylisoxazole
• Synonyms: 5-(3-chlorophenyl)-3-methylisoxazole
• CAS NO: 457654-04-5
• Molecular Formula: C10H8ClNO
• Molecular Weight: 193.62962
• Mol File: 457654-04-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(3-chlorophenyl)-3-methylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-chlorophenyl)-3-methylisoxazole(457654-04-5)
• EPA Substance Registry System: 5-(3-chlorophenyl)-3-methylisoxazole(457654-04-5)

Safety Data

• Hazardous Substances Data: 457654-04-5(Hazardous Substances Data)

Upstream product

• 535-80-8 3-chlorobenzoate 
• 2905-65-9 methyl 3-chlorobenzoate 
• 127-06-0 acetone oxime 

Relevant articles and documents

New isoxazole derivatives designed as nicotinic acetylcholine receptor ligand candidates

In this work we report the synthesis and evaluation of the analgesic properties of new isosteric heterocyclic derivatives, presenting the isoxazole nucleus, designed as nicotinic acetylcholine receptor ligand candidates, analogues to alkaloid epibatidine. Compound 2-(3-methyl-5-isoxazolyl)pyridine (3) presented the best analgesic profile of this series in hot plate test, which was partially prevented by pretreatment with nicotinic receptor antagonist mecamylamine.