4582-65-4

Basic information

• Product Name: 2-Propynoic acid, 3-(2-furanyl)-
• CAS NO: 4582-65-4
• Molecular Formula: C7H4O3
• Molecular Weight: 136.107
• Mol File: 4582-65-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propynoic acid, 3-(2-furanyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynoic acid, 3-(2-furanyl)-(4582-65-4)
• EPA Substance Registry System: 2-Propynoic acid, 3-(2-furanyl)-(4582-65-4)

Safety Data

• Hazardous Substances Data: 4582-65-4(Hazardous Substances Data)

Upstream product

• 38898-09-8 ethyl 3-(furan-2-yl)prop-2-ynoate 
• 584-12-3 2-bromofuran 
• 471-25-0 Propiolic acid 
• 3199-47-1 (5-bromo-[2]furyl)-propiolic acid 

Downstream Products

• 1224168-97-1 2-(2-(4-methoxyphenyl)ethynyl)furan 
• 1217554-43-2 1-(4-methoxyphenyl)-4-(2-furfuryl)buta-1,3-diyne 
• 131292-13-2 ethyl 5-(2-furyl)-3-oxo-2-triphenylphosphoranylidenepent-4-ynoate 
• 1334220-39-1 1-nitro-4-(2'-furfurylethynyl)benzene 

Relevant articles and documents

Enantioselective hydroesterificative cyclization of 1,6-enynes to chiral γ-lactams bearing a quaternary carbon stereocenter

A palladium-catalyzed asymmetric hydroesterification-cyclization of 1,6-enynes with CO and alcohol was developed to efficiently prepare a variety of enantioenriched γ-lactams bearing a chiral quaternary carbon center and a carboxylic ester group. The approach featured good to high chemo-, region-, and enantioselectivities, high atom economy, and mild reaction conditions as well as broad substrate scope. The correlation between the multiple selectivities of such process and the N-substitutes of the amide linker in the 1,6-enyne substrate has been depicted by the crystallographic evidence and control experiments.