4584-39-8

Usage

Molecular structure

Consists of an indole ring with a carboxylic acid substituent at the 3-position, a 1-[(4-chlorophenyl)methyl]-5-methoxy-2-methylgroup, which includes a methyl and a methoxy side chain attached to a phenyl ring.

Derivative

Synthetic derivative of the natural plant hormone indole-3-acetic acid (IAA).

Agricultural use

Has been studied for its potential use as a plant growth regulator.

Pharmaceutical research

Has been studied for its potential anti-inflammatory and anti-cancer properties.

Upstream product

• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 17536-38-8 ethyl 2-(5-methoxy-2-methyl-1H-indol-3-yl)acetate 
• 2882-15-7 5-Methoxy-2-methylindole-3-acetic acid 

Relevant academic research and scientific papers

Luminescent iridium(iii) complexes as COX-2-specific imaging agents in cancer cells

Two luminescent iridium(iii) complexes, 1 and 2, were synthesized and evaluated for their ability to probe COX-2 in human cancer cells. This is the first application of iridium(iii) complexes as imaging agents for COX-2. We demonstrate that complex 1 diff

Synthesis of indomethacin analogues for evaluation as modulators of MRP activity

Synthesis of a range of indomethacin analogues, required for investigation in combination toxicity assays, bearing both N-benzyl and N-benzoyl groups, is described. Copyright

1H-INDOLE-3-ACETIC ACID HYDRAZIDE SPLA2 INHIBITORS

A class of novel 1H-indole-3-acetic acid hydrazides is disclosed together with the use of such indole compounds for inhibiting sPLA2 mediated release of fatty acids (e.g., arachidonic acid) for treatment of conditions such as septic shock

Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids and pharmaceutical compositions thereof

Novel esters of the general formula STR1 in which STR2 is the acyl residue of a non-steroidal anti-inflammatory compound containing a carboxylic acid function. The novel esters are prepared by reacting an acide R--COOH when R is as above, with 1-haloethyl ethyl carbonate. There are also provided pharmaceutical compositions containing any of the said novel esters.