458532-99-5 Usage
General Description
3-Bromopyridin-4-ylboronic Acid is a chemical compound mainly used in various organic syntheses and pharmaceutical research. It is an organoboron compound also known as an arylboronic acid, which is often used as a reagent in Suzuki-Miyaura cross-coupling reactions. These reactions are extremely useful in creating carbon-carbon bonds, an integral process in the development of potential therapeutic agents in medicinal chemistry. This chemical is also known for its high stability and selectivity, and its molecular structure consists of a pyridine ring, which provides a platform for various chemical modifications. 3-BROMOPYRIDIN-4-YLBORONIC ACID must be handled and stored carefully due to its sensitive and potentially hazardous properties.
Check Digit Verification of cas no
The CAS Registry Mumber 458532-99-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,8,5,3 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 458532-99:
(8*4)+(7*5)+(6*8)+(5*5)+(4*3)+(3*2)+(2*9)+(1*9)=185
185 % 10 = 5
So 458532-99-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H5BBrNO2/c7-5-3-8-2-1-4(5)6(9)10/h1-3,9-10H
458532-99-5Relevant articles and documents
Synthesis of novel halopyridinylboronic acids and esters. Part 3: 2, or 3-Halopyridin-4-yl-boronic acids and esters
Bouillon, Alexandre,Lancelot, Jean-Charles,Collot, Valérie,Bovy, Philippe R,Rault, Sylvain
, p. 4369 - 4373 (2007/10/03)
This paper describes a general method for the synthesis and the isolation of novel 2, or 3-halopyridin-4-yl-boronic acids and esters 12-14, 18-20. These compounds are prepared taking in account a regioselective halogen-metal exchange using nBuLi or direct