459143-40-9Relevant academic research and scientific papers
Synthesis of (1S,2R)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecar-boxamide (PPDC) derivatives modified at the carbamoyl moiety as a new class of NMDA receptor antagonists
Kazuta, Yuji,Tsujita, Ryuichi,Ogawa, Kiyoshi,Hokonohara, Tadami,Yamashita, Kanako,Morino, Kiyoko,Matsuda, Akira,Shuto, Satoshi
, p. 1777 - 1791 (2007/10/03)
(1S,2R)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC, 4a), which is a conformationally restricted analogue of the antidepressant milnacipran [(±)-1], represents a new class of potent NMDA receptor antagonists. A series of PPDC a
