459424-41-0

Usage

Uses

Used in Pharmaceutical Production:
2-Fluoro-2-bromo-ethanol is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical properties allow for the creation of complex organic molecules that can be used to develop new drugs and improve existing ones.
Used in Agrochemical Production:
In the agrochemical industry, 2-Fluoro-2-bromo-ethanol serves as a reagent for the synthesis of various agrochemicals, including pesticides and herbicides. Its incorporation into these products can enhance their effectiveness and selectivity, leading to improved agricultural outcomes.
Used in Organic Chemical Synthesis:
Beyond its applications in pharmaceuticals and agrochemicals, 2-Fluoro-2-bromo-ethanol is also utilized in the synthesis of other organic chemicals. Its versatility as a reagent makes it a valuable component in the production of specialty chemicals and materials for various industries.

Upstream product

• 401-55-8 ethyl bromofluoroacetate 
• 684-89-9 methyl 2-bromo-2-fluoroacetate 

Relevant academic research and scientific papers

Method for preparing cis-1-amino-2-fluorocyclopropane

The invention provides a method for preparing cis-1-amino-2-fluorocyclopropane. A preparation process comprises 8 to 10 steps. A structural formula of the cis-1-amino-2-fluorocyclopropane is represented by a formula 1 shown in the description, and the form of benzene sulfonate or hydrochloride is relatively common. An important intermediate product, i.e., cis-fluoro-amine olefin 2 is synthesized. The method has the advantages that the consumption of diiodo-fluoromethane or dibromo-fluoromethane, which is expensive in price and causes heavy pollution in a raw material production process, is avoided; a cis triatomic ring is obtained through the cyclization of high-activity cis-olefin 2, and an absolute-configuration product can be obtained by only one-time resolution, so that the method has especially great advantages in the aspect of either economical efficiency of the raw materials, or the difficulty of resolution of isomers.

Design and synthesis of novel fluoropeptidomimetics as potential mimics of the transition state during peptide hydrolysis

α-Fluoroamino acids were targeted in our ongoing efforts to design novel fluoropeptidomimetics (1) as potential protease inhibitors. α-Fluoroglycine derivative (2) and α-fluoro-β-aminoethanethiol derivatives (3-9) were synthesized for the first time en ro