459452-47-2Relevant academic research and scientific papers
Synthesis of a calothrixin B isomer with a novel 7H-indolo[2,3-j] phenanthridine-7,13(8H)-dione structure
Maingot, Lucie,Thuaud, Frédéric,Sissouma, Drissa,Collet, Sylvain,Guingant, André,Evain, Michel
, p. 263 - 267 (2008/09/21)
Synthesis of an N-protected 2-bromo- 1H-carbazole-1,4(9H)-dione is reported for the first time. We took full advantage of the high polarization and electrophilic properties of this new compound to engage it in a regioselective hetero-Diels-Alder reaction. The resultant cycloadduct was next transformed to an isomer of the naturally occurring calothrixin B displaying a new 7H-indolo[2,3-j]phenanthridine-7,13(8H)-dione structure. Georg Thieme Verlag Stuttgart.
Synthesis of carbazolequinone derivatives as inhibitors of Toxoplasma gondii purine nucleoside phosphorylase
Bouaziz, Zouhair,Gherardi, Arnaud,Regnier, Francois,Sarciron, Marie-Elizabeth,Bertheau, Xavier,Fenet, Bernard,Walchshofer, Nadia,Fillion, Houda
, p. 1834 - 1838 (2007/10/03)
9-Ethyl-6-hydroxycarbazolequinone (9) was synthesized and submitted to a hetero Diels-Alder reaction towards azadienes 10a or 10b to afford the hydroxypyridocarbazole-5,11-diones 11 or 12a,b. A Bracher cyclization applied to compound 12b led to the 9-hydr
