4595-82-8Relevant academic research and scientific papers
CYCLIC RENIN INHIBITORS CONTAINING 2-SUBSTITUTED (3S,4S)-4-AMINO-5-CYCLOHEXYL-3-HYDROXY PENTANOIC ACID, 2-SUBSTITUTED (3S,4S)-5-CYCLOHEXYL-3,4-DI-HYDROXY PENTANOIC ACID OR 2-SUBSTITUTED (4S,5S)-5-AMINO-6-CYCLOHEXYL-4-HYDROXYHEXANOIC ACID OR ITS ANALOGS
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, (2008/06/13)
Compounds of the formula STR1 are disclosed. These compounds inhibit the angiotensinogen-cleaving action of the natural proteolytic enzyme, renin, are useful in treating, preventing or managing renin-associated hypertension, hyperaldosteronism, congestive heart failure, and glaucoma.
CYCLIC RENIN INHIBITORS CONTAINING 3(S)-AMINO-4-CYCLOHEXYL-2(R)-HYDROXY-BUTANOIC ACID OR 4-CYCLO-HEXYL-(2R,3S)-DIHYDROXYBUTANOIC ACID OR RELATED ANALOGS
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, (2008/06/13)
Compounds of the formula: STR1 are disclosed. These compounds inhibit the angiotensinogen-cleaving action of the natural proteolytic enzyme, renin, and are useful in treating, preventing or managing renin-associated hypertension, hyperaldosteronism, congestive heart failure, and glaucoma.
Cyclic renin inhibitors
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, (2008/06/13)
Compounds of the formula: are disclosed. These compounds inhibit the angiotensinogen-cleaving action of the natural proteolytic enzyme, renin, and are useful in treating, preventing or managing renin-associated hypertension, hyperaldosteronism, congestive
Macrocyclic lactones having renin inhibiting properties
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, (2008/06/13)
Compounds of the formula:
Synergistin derivatives and pharmaceutical compositions which contain them
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, (2008/06/13)
The invention provides new synergistin derivatives of formula STR1 in which Y is hydrogen or dimethylamino and R is a 3- or 4-quinuclidinyl radical, the isomers thereof and their mixtures, and their salts, also the preparation thereof. These compounds may
