45952-56-5

Basic information

• Product Name: Phenol, 4-(bromomethyl)-2,6-dimethyl-
• Synonyms: 4-bromomethyl-2,6-dimethylphenol;4-Hydroxy-3.5-dimethyl-benzylbromid;4-Brommethyl-2,6-dimethyl-phenol;4-Hydroxy-3.5-dimethyl-1-brommethyl-benzol;3,5-dimethyl-4-hydroxybenzyl bromide
• CAS NO: 45952-56-5
• Molecular Formula: C9H11BrO
• Molecular Weight: 215.09
• Mol File: 45952-56-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(bromomethyl)-2,6-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(bromomethyl)-2,6-dimethyl-(45952-56-5)
• EPA Substance Registry System: Phenol, 4-(bromomethyl)-2,6-dimethyl-(45952-56-5)

Safety Data

• Hazardous Substances Data: 45952-56-5(Hazardous Substances Data)

Upstream product

• 4397-14-2 4-(hydroxymethyl)-2,6-dimethylphenol 
• 87025-08-9 4-bromo-2,4,6-trimethylcyclohexa-2,5-dienone 
• 527-60-6 Mesitol 
• 576-26-1 2.6-dimethylphenol 

Downstream Products

• 5384-21-4 bis(4-hydroxy-3,5-dimethylphenyl)methane 
• 54812-20-3 4-Acetoxymethyl-2,6-dimethyl-phenol 
• 25347-59-5 3,5,3',5'-tetramethyl-stilbene-4,4'-diol 
• 6476-26-2 4,4’-(ethane-1,2-diyl)bis(2,6-dimethylphenol) 
• 59869-79-3 3,3',5,5'-tetramethylstilbene-4,4'-quinone 
• 107140-21-6 2,6-dimethyl-4-(3,5-dimethyl-4-hydroxybenzylidene)-2,5-cyclohexadien-1-one 
• 527-60-6 Mesitol 
• 95164-86-6 4,4'-diacetoxy-3,5,3',5'-tetramethyl-stilbene 
• 115020-81-0 bis-(4-acetoxy-3,5-dimethyl-phenyl)-methane 
• 106713-67-1 (3,5,3',5'-tetramethyl-bibenzyldiyl-(4,4'))-diacetate 
• 2233-18-3 4-hydroxy-3,5-dimethylbenzaldehyde 
• 711-95-5 acetic acid-(4-bromomethyl-2,6-dimethyl-phenyl ester) 

Relevant articles and documents

Synthesis of novel water soluble benzylazolium prodrugs of lipophilic azole antifungals

Water soluble N-benzyltriazolium or N-benzylimidazolium salt type prodrugs of several highly lipophilic triazole or imidazole antifungals have been synthesized. They were designed to undergo an enzymatic activation followed by a self-cleavage to release a

ipso Halogenation. II. Bromination of phenols, isomerisation and disproportionation of bromophenols, and dione-phenol rearrangement of bromodienones

Bromination of p-cresol, bromo-p-cresol, 3,4-dimethylphenol, and mesitol in trifluoromethanesulfonic acid gices as the main product the bromo derivative with bromine meta to hydroxyl, a result attributed to the intermediate formation of a bromodienone and its rearrangement.Phenols does not give m-bromophenol in trifluoromethanesulfonic acid. 4-Bromo-2,4,6-trimethylcyclohexa-2,5-dienone rearranges to 3-bromomesitol in trifluoromethanesulfonic acid and, similarly, 2,4,6-tribromo-4-methylcyclohexa-2,5-dienone rearranges to 3-bromomesitol in trifluoromethanesulfonic acid and, similarly, 2,4,6-tribromo-4-methylcyclohexa-2,5-dienone rearranges to 2,3,6-tribromo-4-methylphenol.Under appropriate conditions debromination of bromodienones is competitive with rearrangement.Tetramethylammonium bromide in trifluoromethanesulfonic acid is an effective reagent for isomerization and disproportionation of bromophenols.Tetramethylammonium iodide in trifluoromethanesulfonic acid is an effective reagent for selective debromination of bromophenols at the ortho and para position.