459810-37-8

Basic information

• Product Name: C₃₄H₂₇ClO₉
• Synonyms: C₃₄H₂₇ClO₉
• CAS NO: 459810-37-8
• Molecular Weight: 615.036
• Mol File: 459810-37-8.mol

Chemical Properties

• CAS DataBase Reference: C₃₄H₂₇ClO₉(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₄H₂₇ClO₉(459810-37-8)
• EPA Substance Registry System: C₃₄H₂₇ClO₉(459810-37-8)

Safety Data

• Hazardous Substances Data: 459810-37-8(Hazardous Substances Data)

Upstream product

• 96996-90-6 1,2,3,4,6-penta-O-benzoyl-α,β-D-mannopyranoside 

Downstream Products

• 459810-17-4 C₄₂H₃₆O₁₁ 
• 459810-21-0 (2R,4aR,6S,7S,8S,8aR)-7-Benzyloxy-6-(4-methoxy-benzyloxy)-2-phenyl-8-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-hexahydro-pyrano[3,2-d][1,3]dioxine 
• 459810-20-9 (2R,4aR,6S,7S,8S,8aS)-7-Benzyloxy-6-(4-methoxy-benzyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol 
• 459810-19-6 (2R,4aR,6S,7S,8R,8aS)-6-(4-Methoxy-benzyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-7,8-diol 
• 459810-22-1 (2R,4aR,6S,7S,8S,8aR)-7-Benzyloxy-2-phenyl-8-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-6-ol 

Relevant articles and documents

Synthesis of a molecular mimic of the Glc1Man9 oligoside as potential inhibitor of calnexin binding to ΔF508 CFTR protein

Deletion of phenylalanine at position 508 of the CFTR protein is associated with a severe form of cystic fibrosis. Biosynthetic arrest of the misfolded ΔF508 CFTR protein in the endoplasmic reticulum is due to prolonged interaction with protein chaperones. In order to overcome this retention and thereby restore the delivery of the protein to the plasma membrane, a molecular mimic of the glycoprotein oligoside moiety has been designed and synthesized. Ability of this mimic to inhibit the binding of the natural Glc1Man9GlcNAc oligoside to calnexin has been measured.