459820-54-3Relevant academic research and scientific papers
Palladium-assisted formation of carbon-carbon bonds. Part 10. Insertion reactions of isocyanides into the Pd-C bond of orthopalladated primary amines. Synthesis of 2-R-aminoisoindolinium salts (R = tBu, 2,6-xylyl)
Vicente, José,Saura-Llamas, Isabel,Grünwald, Claus,Alcaraz, Carmen,Jones, Peter G.,Bautista, Delia
, p. 3587 - 3595 (2008/10/08)
Palladium assisted formation of carbon-carbon bonds was discussed. Insertion reactions of isocyanides into the Pd-C bond of orthopalladated primary amines and synthesis of 2-R-aminoisoindolinium salts were performed. Results showed that formation of this complex requires coordination of a second molecule of isocyanide per palladium through a bridge splitting process.
