460090-24-8 Usage
General Description
1,2-Cyclohexanediamine, N-methyl, (1R,2R)-rel-(9CI) is a chemical compound also known as N-methyl-1,2-cyclohexanediamine. It is a chiral compound, meaning it has two non-superimposable mirror image forms, known as enantiomers, which are denoted as (1R,2R)-rel-(9CI) and (1S,2S)-rel-(9CI). 1,2-Cyclohexanediamine,N-methyl-,(1R,2R)-rel-(9CI) is used as a building block in the synthesis of various pharmaceuticals and agrochemical products. It is a primary diamine with a cyclic structure, making it a versatile intermediate for the production of polyurethane, nylon, and other polymers. Its chiral nature also makes it valuable in asymmetric synthesis for the production of optically pure compounds. The compound is subject to strict regulations due to its potential environmental and health hazards, and as such, its production and use are carefully controlled.
Check Digit Verification of cas no
The CAS Registry Mumber 460090-24-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,0,0,9 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 460090-24:
(8*4)+(7*6)+(6*0)+(5*0)+(4*9)+(3*0)+(2*2)+(1*4)=118
118 % 10 = 8
So 460090-24-8 is a valid CAS Registry Number.
460090-24-8Relevant articles and documents
Facile cleavage of Si-C bonds during the sol-gel hydrolysis of aminomethyltrialkoxysilanes - A new method for the methylation of primary amines
Adima, Augustin,Bied, Catherine,Moreau, Joel J. E.,Man, Michel Wong Chi
, p. 2582 - 2588 (2007/10/03)
The reaction of chloromethyltriethoxysilane with (1R,2R)-bis(methylamino) cyclohexane (1) afforded the corresponding bis-silylated compound 2. The sol-gel hydrolysis of 2 did not give the expected bridged silsesquioxane owing to quantitative Si-C-bond cleavage. Instead, silica and (1R,2R)-bis(dimethylamino) cyclohexane (3) were obtained. This reaction was exploited to propose a new route for the methylation of amines. Such methylation reaction of amines could be extended to other amines and provides a new method for the selective monomethylation of primary amines. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
