460313-75-1

Upstream product

• 460313-72-8 (3'R,4''S)-3-[3'-benzyloxyamino-3'-(2'',2''-dimethyl-1'',3''-dioxolan-4''-yl)propanoyl]oxazolidin-2-one 
• 460313-70-6 (4''S)-(E)-3-[3'-(2'',2''-dimethyl-1'',3''-dioxolan-4''-yl)-2-propenoyl]oxazolidin-2-one 
• 460313-71-7 (4''S)-(Z)-3-[3'-(2'',2''-dimethyl-1'',3''-dioxolan-4''-yl)-2-propenoyl]oxazolidin-2-one 
• 1027072-99-6 C₁₃H₂₀O₆ 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 123620-85-9 (4'S)-(Z)-3-(2',2'-dimethyl-1',3'-dioxolan-4'-yl)-2-propenoic acid 
• 81703-94-8 methyl (2Z)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate 

Downstream Products

• 460313-74-0 methyl (3R,4'S)-3-benzyloxyamino-3-(2',2'-dimethyl-1',3'-dioxolan-4'yl)propionate 

Relevant academic research and scientific papers

Lewis acid-promoted synthesis and reactivity of β-O-benzylhydroxylamino imides derived from D-glyceraldehyde

This paper describes the synthesis and use β-hydroxylamino imides derived from D-glyceraldehyde possessing a number of reactive sites that operate synergistically or alternatively to bring about highly regio- and diastereoselective transformations to give an optically pure aziridine-2-imide, a dihydro pyrimidine-2,4-dione, or a lactone. Both the syntheses, via the diastereoselective 1,4-conjugate addition of O-benzyl hydroxylamine to α,β-unsaturated imides, and transformations can be simply tuned by choosing between different Lewis acids.