460355-04-8

Basic information

• Product Name: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-indole-3-carbaldehyde
• Synonyms: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-indole-3-carbaldehyde
• CAS NO: 460355-04-8
• Molecular Weight: 563.65
• Mol File: 460355-04-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-indole-3-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-indole-3-carbaldehyde(460355-04-8)
• EPA Substance Registry System: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-indole-3-carbaldehyde(460355-04-8)

Safety Data

• Hazardous Substances Data: 460355-04-8(Hazardous Substances Data)

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 460355-03-7 1-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-indole-3-carbaldehyde 
• 487-89-8 Indole-3-carboxaldehyde 
• 52162-55-7 2-deoxy-3,5-di-O-(p-toluoyl)-α-D-erythro-pentofuranosyl chloride 

Relevant articles and documents

A facile incorporation of the aldehyde function into DNA: 3-Formylindole nucleoside as an aldehyde-containing universal nucleoside

The first facile incorporation of an aldehyde function into DNA without any protection/deprotection of the aldehyde was achieved by the use of 3-formylindole 2′-deoxynucleoside (1). This building block is very easily prepared and efficiently incorporated into oligonucleotides. In addition, 1 acted as a universal nucleoside in duplex. The post-synthetic modification of oligonucleotides bearing 1 with functionalized molecules was also effective.