460356-06-3

Upstream product

• 88337-87-5 methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1->3)-2,4-di-O-benzoyl-α-L-rhamnopyranoside 
• 28915-80-2 2,3,4-tri-O-acetyl-L-rhamnopyranose 
• 460356-05-2 methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1->3)-α-L-rhamnopyranoside 
• 113893-72-4 2,3,4-tri-O-acetyl-L-rhamnopyranosyl trichloroacetimidate 
• 7404-35-5 1,2,3,4-tetra-O-acetyl-L-rhamnopyranose 
• 73-34-7 L-rhamnose 

Downstream Products

• 460356-07-4 methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1->3)-α-L-rhamnopyranosyl-(1->3)-2,4-di-O-benzoyl-α-L-rhamnopyranoside 
• 578731-61-0 methyl 2,3,4-tri-O-benzoyl-α-L-rhamnopyranosyl-(1->3)-2,4-di-O-benzoyl-α-L-rhamnopyranosyl-(1->2)-3,4-di-O-benzoyl-α-L-rhamnopyranosyl-(1->3)-α-L-rhamnopyranosyl-(1->3)-2,4-di-O-benzoyl-α-L-rhamnopyranoside 

Relevant academic research and scientific papers

Synthesis of a xylosylated rhamnose pentasaccharide - The repeating unit of the O-specific side chain of lipopolysaccharides from the reference strains for Stenotrophomonas maltophilia serogroup O18

A xylosylated rhamnose pentasaccharide, α-L-Rhap-(1→3)-[β-L-Xylp-(1→ 2)-] [β-L-Xylp-(1→4)-]α-L-Rhap-(1→3)-L-Rhap, the repeating unit of the O-specific side chain of the lipopolysaccharides from the reference strains for Stenotrophomonas maltophilia serogroup O18, was synthesized by a highly regio- and stereoselective procedure. Thus coupling of methyl rhamnopyranoside (9) with 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl trichloroacetimidate (8) gave the (1→3)-linked disaccharide (10), and subsequent benzoylation and deacetylation afforded the disaccharide acceptor 12. Condensation of 12 with 8 yielded methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1→3)-α-L- rhamnopyranosyl-(1→3)-2,4-di-O-benzoyl-α-L-rhamnopyranoside (13). Coupling of 13 with 2,3,4-tri-O-benzoyl-α-L-xylopyranosyl trichloroacetimidate (4) followed by deprotection gave the target pentasaccharide (15).