460740-16-3

Basic information

• Product Name: (2S)-2-hydroxy-8-methoxy-1,2,3,4-tetrahydronaphthalene
• CAS NO: 460740-16-3
• Molecular Weight: 178.231
• Mol File: 460740-16-3.mol

Chemical Properties

• CAS DataBase Reference: (2S)-2-hydroxy-8-methoxy-1,2,3,4-tetrahydronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-2-hydroxy-8-methoxy-1,2,3,4-tetrahydronaphthalene(460740-16-3)
• EPA Substance Registry System: (2S)-2-hydroxy-8-methoxy-1,2,3,4-tetrahydronaphthalene(460740-16-3)

Safety Data

• Hazardous Substances Data: 460740-16-3(Hazardous Substances Data)

Upstream product

• 460740-13-0 (1R,2S)-1,2-dihydroxy-8-methoxy-1,2,3,4-tetrahydronaphthalene 

Downstream Products

• 1374429-01-2 (S)-((S)-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl) 3,3,3-trifluoro-2-methoxy-2-phenylpropanoate 
• 127165-18-8 (2R)-2-amino-8-methoxy-1,2,3,4-tetrahydronaphthalene 

Relevant articles and documents

A chemoenzymatic synthesis of (2R)-8-substituted-2-aminotetralins

(2R)-2-Amino-8-methoxy-1,2,3,4-tetrahydronaphthalene, a useful precursor of the 5-hydroxytryptamine receptor agonist 8-OH-DPAT ((2R)-2-(dipropylamino)-8-hydroxytetrahydronaphthalene), has been synthesized from 1-methoxynaphthalene through a chemoenzymatic protocol. The same protocol has been subsequently applied to the synthesis of other (2R)-2-amino-1,2,3,4-tetrahydronaphthalenes.