460744-02-9Relevant academic research and scientific papers
Catecholic flavonoids acting as telomerase inhibitors
Menichincheri, Maria,Ballinari, Dario,Bargiotti, Alberto,Bonomini, Luisella,Ceccarelli, Walter,D'Alessio, Roberto,Fretta, Antonella,Moll, Juergen,Polucci, Paolo,Soncini, Chiara,Tibolla, Marcellino,Trosset, Jean-Yves,Vanotti, Ermes
, p. 6466 - 6475 (2007/10/03)
In recent years telomerase has been identified as a new promising target in oncology and consequently new telomerase inhibitors have been intensely explored as anticancer agents. Focused screening of several polyhydroxylated flavonoids has allowed us to i
Substituted benzopyranones as telomerase inhibitors
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, (2008/06/13)
The present invention relates to benzopyranone derivatives, to methods for treating telomerase-modulated diseases, in particular cancers, with said derivatives, to a process for their preparation, to their use as medicaments and to pharmaceutical compositions comprising them.
