460748-85-0 Usage
Uses
Used in Pharmaceutical Chemistry:
(S)-2-(fluoroMethyl)pyrrolidine is used as a building block for the synthesis of various pharmaceutical compounds due to its unique structure and properties. The fluoromethyl group enhances the reactivity and stability of the molecule, making it a promising candidate for the development of new drugs with improved efficacy and selectivity.
Used in Medicinal Applications:
In the field of medicine, (S)-2-(fluoroMethyl)pyrrolidine is utilized as a key intermediate in the production of therapeutic agents. Its chiral nature allows for the creation of enantiomer-specific drugs, which can exhibit different pharmacological activities and reduce potential side effects associated with racemic mixtures.
Used in Drug Development:
(S)-2-(fluoroMethyl)pyrrolidine plays a crucial role in drug development as a versatile starting material for the synthesis of novel pharmaceuticals. Its unique properties, including the presence of the fluorine atom, enable the design of drugs with enhanced bioavailability, metabolic stability, and target specificity.
Used in Chemical Research:
(S)-2-(fluoroMethyl)pyrrolidine is also employed as a research tool in chemical laboratories, where it can be used to study the effects of fluorination on the properties and reactivity of organic compounds. This knowledge can be applied to the development of new synthetic methods and the optimization of existing ones.
Used in the Synthesis of Advanced Materials:
The unique properties of (S)-2-(fluoroMethyl)pyrrolidine make it a valuable component in the development of advanced materials with specific applications in various industries, such as electronics, aerospace, and automotive. The fluorine atom can impart desirable characteristics, such as increased thermal stability and reduced friction, to these materials.
Check Digit Verification of cas no
The CAS Registry Mumber 460748-85-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,0,7,4 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 460748-85:
(8*4)+(7*6)+(6*0)+(5*7)+(4*4)+(3*8)+(2*8)+(1*5)=170
170 % 10 = 0
So 460748-85-0 is a valid CAS Registry Number.
460748-85-0Relevant academic research and scientific papers
4-[6-(2-Aminoethyl)naphthalen-2-yl]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration
Black, Lawrence A.,Nersesian, Diana L.,Sharma, Padam,Ku, Yi-Yin,Bennani, Youssef L.,Marsh, Kennan C.,Miller, Thomas R.,Esbenshade, Timothy A.,Hancock, Arthur A.,Cowart, Marlon
, p. 1443 - 1446 (2007/10/03)
4-[6-(2-Tertiaryaminoethyl)naphthalen-2-yl]benzonitriles are conformationally constrained histamine H3 receptor antagonists with high potency and selectivity. The analogs were designed around a naphthalene core, with the goal of enhancing lipop
Novel amines as histamine-3 receptor ligands and their therapeutic applications
-
, (2008/06/13)
Compounds of formula (I) or a pharmaceutically acceptable salts or prodrug thereof which are useful for the modulation of the histamine-3 receptors in mammals and which are useful for the treatment of disorders ameliorated by histamine-3 receptor ligands.
