46118-11-0 Usage
Heterocyclic compound
Contains a pyrimidine ring with a hydroxy group at the 4th position and a carbonitrile group at the 5th position
Substitution
Ethylthio group is attached to the 2nd position of the pyrimidine ring
Potential applications
Pharmaceutical and agrochemical industries
Use as building block
Synthesis of various pharmaceutical drugs and agrochemicals
Biological activity
Potential for further research and development
Check Digit Verification of cas no
The CAS Registry Mumber 46118-11-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,6,1,1 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 46118-11:
(7*4)+(6*6)+(5*1)+(4*1)+(3*8)+(2*1)+(1*1)=100
100 % 10 = 0
So 46118-11-0 is a valid CAS Registry Number.
46118-11-0Relevant academic research and scientific papers
Src kinase inhibitor compounds
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, (2008/06/13)
Pyrimidine compounds (Formula I), or their pharmaceutically acceptable salts, hydrates, solvates, crystal forms and individual diastereomers, and pharmaceutical compositions including the same, which are inhibitors of tyrosine kinase enzymes, and as such are useful in the prophylaxis and treatment of protein tyrosine kinase-associated disorders, such as immune diseases, hyperproliferative disorders and other diseases in which inappropriate protein kinase action is believed to play a role, such as cancer, angiogensis, atheroscelerosis, graft rejection, rheumatoid arthritis and psoriasis.
