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1-[1-(2-hydroxyphenyl)ethyl]piperidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

461389-79-7

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461389-79-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 461389-79-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,1,3,8 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 461389-79:
(8*4)+(7*6)+(6*1)+(5*3)+(4*8)+(3*9)+(2*7)+(1*9)=177
177 % 10 = 7
So 461389-79-7 is a valid CAS Registry Number.

461389-79-7Downstream Products

461389-79-7Relevant academic research and scientific papers

Synthesis and cholinesterase activity of phenylcarbamates related to Rivastigmine, a therapeutic agent for Alzheimer's disease

Mustazza, Carlo,Borioni, Anna,Giudice, Maria Rosaria Del,Gatta, Franco,Ferretti, Rosella,Meneguz, Annarita,Volpe, Maria Teresa,Lorenzini, Paola

, p. 91 - 109 (2007/10/03)

In order to develop new cholinesterase agents effective against Alzheimer's disease (AD) we synthesized some phenylcarbamates structurally related to Rivastigmine and evaluated their in vitro and in vivo biological activity. Among the compounds which displayed the most significant in vitro activity, 1-[1-(3-dimethylcarbamoyloxyphenyl)ethyl]piperidine (31b), in addition to a simple and cheaper synthesis, showed lower toxicity and very similar therapeutic index in comparison with Rivastigmine.

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