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7-fluoro-1-(2-fluoro-phenyl)-9H-β-carboline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 461424-18-0 Structure
  • Basic information

    1. Product Name: 7-fluoro-1-(2-fluoro-phenyl)-9H-β-carboline
    2. Synonyms:
    3. CAS NO:461424-18-0
    4. Molecular Formula:
    5. Molecular Weight: 280.277
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 461424-18-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-fluoro-1-(2-fluoro-phenyl)-9H-β-carboline(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-fluoro-1-(2-fluoro-phenyl)-9H-β-carboline(461424-18-0)
    11. EPA Substance Registry System: 7-fluoro-1-(2-fluoro-phenyl)-9H-β-carboline(461424-18-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 461424-18-0(Hazardous Substances Data)

461424-18-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 461424-18-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,1,4,2 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 461424-18:
(8*4)+(7*6)+(6*1)+(5*4)+(4*2)+(3*4)+(2*1)+(1*8)=130
130 % 10 = 0
So 461424-18-0 is a valid CAS Registry Number.

461424-18-0Downstream Products

461424-18-0Relevant articles and documents

β-Carbolines as specific inhibitors of cyclin-dependent kinases

Song, Yongcheng,Wang, Jian,Teng, Su Fern,Kesuma, Djohan,Deng, Yu,Duan, Jinao,Wang, Jerry H.,Qi, Robert Zhong,Sim, Mui Mui

, p. 1129 - 1132 (2002)

Harmine (3), 7-fluoro-1-methyl β-carboline (35) and 1-(5-methyl-imidazol-4-yl) β-carboline (41) were potent and specific inhibitors of cyclin-dependent kinases. The degree of aromaticity of the tricyclic ring and the positioning of substituents are important for inhibitory activity. While most β-carbolines inhibited CDK2 and CDK5 to the same extent, selective inhibition against CDK2 was observed in 1-(2-chlorophenyl)- (12), 1-(2-fluorophenyl)- (15), and 1-(2-chloro-5-nitrophenyl)- (28) β-carbolines.

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