461644-58-6

Upstream product

• 461644-56-4 (2S,4R,5R)-1,2-O-cyclohexylidene-6-O-(tert-butyldiphenylsilyl)-1,2,5,6-tetrahydroxy-4-(4-methoxyphenyl)hexan-3-one 
• 461644-52-0 1-(S)-1,4-Dioxa-spiro[4.5]dec-2-yl-2-(4-methoxy-phenyl)-ethanol 
• 461644-50-8 1-(S)-1,4-Dioxa-spiro[4.5]dec-2-yl-2-(4-methoxy-phenyl)-ethanone 

Downstream Products

• 237736-16-2 (4R,5R)-5-(tert-butyldiphenylsilyloxymethyl)-4-(4-methoxyphenyl)oxazolidin-2-one 

Relevant academic research and scientific papers

Stereoselective synthesis of (-)-cytoxazone

The stereoselective synthesis of the cytokine modulator (-)-cytoxazone in enantiopure form is described. Key steps of the process are a syn-stereoselective aldol addition of a chiral ketone mediated by chlorodicyclohexylborane, and a Curtius rearrangement