461649-04-7

Basic information

• Product Name: 4-nitrobenzyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-2(R)-methyl-5-oxopyrrolidin-3-ylthio]-1-carbapen-2-em-3-carboxylate
• CAS NO: 461649-04-7
• Molecular Weight: 475.522
• Mol File: 461649-04-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-nitrobenzyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-2(R)-methyl-5-oxopyrrolidin-3-ylthio]-1-carbapen-2-em-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitrobenzyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-2(R)-methyl-5-oxopyrrolidin-3-ylthio]-1-carbapen-2-em-3-carboxylate(461649-04-7)
• EPA Substance Registry System: 4-nitrobenzyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-2(R)-methyl-5-oxopyrrolidin-3-ylthio]-1-carbapen-2-em-3-carboxylate(461649-04-7)

Safety Data

• Hazardous Substances Data: 461649-04-7(Hazardous Substances Data)

Upstream product

• 461648-88-4 5(R)-methyl-4(R)-acetylthiopyrrolidinone 
• 461648-80-6 5(R)-methyl-4(S)hydroxypyrrolidinone 
• 68820-71-3 ethyl 1-[(S)-1-phenylethyl]aziridine-(R)-carboxylate 
• 93711-81-0 (4-nitrophenyl)methyl (4R,5R,6S)-3-[(diphenoxyphosphinyl)oxy]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 461648-95-3 5(R)-methyl-4(R)-thiopyrrolidinone 

Relevant articles and documents

Syntheses of 1beta-methylcarbapenems bearing 5-methyl-4-hydroxypyrrolidinone.

A new series of 1beta-methylcarbapenems 1a-d bearing 5-methyl-4-mercaptopyrrolidinone rings has been prepared and evaluated for in vitro antibacterial activity and pharmacokinetic parameters. Most compounds showed excellent antibacterial activity and high