462-12-4

Basic information

• Product Name: 8-fluoro-3-methyl-octanoic acid
• Synonyms: 8-fluoro-3-methyl-octanoic acid
• CAS NO: 462-12-4
• Molecular Formula: C9H17FO2
• Molecular Weight: 176.2285
• Mol File: 462-12-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 269.6°Cat760mmHg
• Flash Point: 116.8°C
• Appearance: /
• Density: 0.992g/cm³
• Vapor Pressure: 0.00204mmHg at 25°C
• Refractive Index: 1.425
• CAS DataBase Reference: 8-fluoro-3-methyl-octanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 8-fluoro-3-methyl-octanoic acid(462-12-4)
• EPA Substance Registry System: 8-fluoro-3-methyl-octanoic acid(462-12-4)

Safety Data

• Hazardous Substances Data: 462-12-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H17FO2/c1-8(7-9(11)12)5-3-2-4-6-10/h8H,2-7H2,1H3,(H,11,12)

Upstream product

• 27151-65-1 3-methyl-1,5-pentanedioic acid monomethyl ester 
• 407-75-0 5-fluoropentanoic acid 
• 144682-04-2 ethyl 3-methyl-8-(p-toluenesulfonyloxy)octanoate 
• 144681-96-9 ethyl 3-methyl-8-(tetrahydro-2H-pyran-2-yl)oxyoctanoate 
• 98525-84-9 ethyl (E)-8-<(tetrahydro-2'H-pyran-2'-yl)oxy>-2-octenoate 
• 144681-97-0 ethyl 8-hydroxy-3-methyloctanoate 
• 75958-95-1 (E)-8-hydroxy-oct-2-enoic acid ethyl ester 
• 34067-76-0 6-hydroxyhexanal 
• 502-44-3 hexahydro-2H-oxepin-2-one 
• 144682-07-5 ethyl 8-fluoro-3-methyloctanoate 

Relevant articles and documents

Synthesis of ω-fluorinated octanoic acid and its β-substituted derivatives

Simple syntheses are described for the ω-fluorinated analogs of octanoic acid and its β-substituted derivatives in which insertion of a methyl and dimethyl group, and oxygen substitution at the C-3 position are involved, employing nucleophilic displacement with fluoride ion of the tosylate functions in the later stage of synthesis.The synthetic procedures offer easy and convenient acces to the corresponding 18F-labeled analogs using the readily available fluoride ion.