46209-55-6

Basic information

• Product Name: 1-[(5-methylfuran-2-yl)methyl]piperidine
• Synonyms: 1-[(5-Methyl-2-furyl)methyl]piperidine; piperidine, 1-[(5-methyl-2-furanyl)methyl]-
• CAS NO: 46209-55-6
• Molecular Formula: C₁₁H₁₇NO
• Molecular Weight: 179.2588
• Mol File: 46209-55-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 234.1°C at 760 mmHg
• Flash Point: 95.4°C
• Density: 1.024g/cm³
• Vapor Pressure: 0.0539mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: 1-[(5-methylfuran-2-yl)methyl]piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(5-methylfuran-2-yl)methyl]piperidine(46209-55-6)
• EPA Substance Registry System: 1-[(5-methylfuran-2-yl)methyl]piperidine(46209-55-6)

Safety Data

• Hazardous Substances Data: 46209-55-6(Hazardous Substances Data)

Usage

Chemical structure

1-[(5-methylfuran-2-yl)methyl]piperidine is a chemical compound with a unique structure consisting of a piperidine ring and a furan ring.

Classification

It is classified as a piperidine derivative, which is a type of organic compound frequently used in medicinal and chemical applications.

Aromatic properties

The presence of the furan ring suggests potential aromatic and electron-rich properties.

Reactivity

The electron-rich properties of the furan ring can contribute to the reactivity of the molecule.

Biological activity

The unique structure and properties of the molecule may contribute to its biological activity.

Potential applications

1-[(5-methylfuran-2-yl)methyl]piperidine may have potential applications in the pharmaceutical industry for drug development.

Further research

Further research is needed to explore the properties and potential uses of 1-[(5-methylfuran-2-yl)methyl]piperidine.

Upstream product

• 110-89-4 piperidine 
• 534-22-5 2-methylfuran 
• 57846-03-4 2-(bromomethyl)-5-methylfuran 
• 50-00-0 formaldehyd 
• 6091-44-7 piperidine hydrochloride 
• 880-09-1 di(N-piperidinyl)methane 
• 20276-55-5 N-methylenepiperidinium chloride 
• 15622-20-5 1-(piperidinomethyl)-1H-1,2,3-benzotriazole 
• 1197-60-0 methylfurmethide 
• 14496-35-6 N,N-dimethyl-1-(5-methylfuran-2-yl)methanamine 

Relevant articles and documents

Green synthesis method of methyl cyclopentenolone

The invention relates to a green synthesis method of methyl cyclopentenolone, and belongs to the field of organic synthesis. The method comprises the following synthesis steps: A, carrying out Mannichreaction on 2-methyl furan serving as a raw material and piperidine hydrochloride to generate an aminated intermediate; B, adding a catalytic amount of sulfuric acid into the aminated intermediate for reflux reaction to obtain a hydrolysate; and C, adding the hydrolysate into methylbenzene, neutralizing to be neutral by using sodium hydroxide, adding piperidine and pyridine, refluxing and separating water until no water is separated out, and rectifying to obtain a cyclized product; and D, putting the cyclized product into an acetic acid-hydrochloric acid solution for reflux reaction, cooling,removing piperidine hydrochloride, removing acetic acid from the filtrate, adding water, and crystallizing to obtain methyl cyclopentenolone. According to the method, the generation of wastewater andwaste salt is greatly reduced, the generated piperidine hydrochloride can be recycled and reused, and the method is a green synthetic method for synthesizing methyl cyclopentenolone.

aminoalkylbenzotriazoles: Reagents for the aminoalkylation of electron rich heterocycles

Secondary and tertiary aminoalkylbenzotriazoles react with pyrrole, indole, their N-methyl analogs and with 2-methylfuran under mild reaction conditions in the presence of a Lewis acid to afford selectively the corresponding secondary or tertiary amines.