462656-84-4

Upstream product

• 108-24-7 acetic anhydride 
• 236117-59-2 (R)-2-((S)-(tert-Butyl-dimethyl-silanyloxy)-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-methyl)-but-3-en-1-ol 
• 462656-94-6 C₃₁H₄₉NO₇Si 
• 462656-83-3 C₂₅H₃₅NO₇ 
• 132969-60-9 (2S)-3-[(4-methoxybenzyl)oxy]-2-methylpropanal 
• 220213-55-8 (2S,3R)-3-[(S)-2-(4-Methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxirane-2-carbaldehyde 
• 220213-63-8 {(2R,3R)-3-[(S)-2-(4-Methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-methanol 

Downstream Products

• 462656-85-5 C₂₆H₄₂O₇Si 
• 236117-62-7 Acetic acid (2S,3R,4R,5S)-2-((S)-(tert-butyl-dimethyl-silanyloxy)-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-methyl)-5-hydroxy-4,8-dimethyl-7-oxo-3-triethylsilanyloxy-nonyl ester 
• 236117-60-5 C₃₀H₅₀O₇Si 
• 236117-56-9 Acetic acid (2S,3S,4S)-2-((S)-(tert-butyl-dimethyl-silanyloxy)-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-methyl)-4-methyl-5-oxo-3-triethylsilanyloxy-pentyl ester 

Relevant academic research and scientific papers

Studies on the synthesis of tedanolide: synthesis of the C(5)-C(21) segment via a highly stereoselective fragment assembly aldol reaction of a chiral beta,gamma-unsaturated methyl ketone.

[formula: see text] A highly diastereoselective synthesis of 3, corresponding to the C(5)-C(21) segment of tedanolide, has been accomplished by a route utilizing the aldol reaction of aldehyde 4 and the beta,gamma-unsaturated methyl ketone 5.