46278-13-1Relevant academic research and scientific papers
Synthesis of (-)-pericosine B, the antipode of the cytotoxic marine natural product
Usami, Yoshihide,Suzuki, Kentaro,Mizuki, Koji,Ichikawa, Hayato,Arimoto, Masao
experimental part, p. 315 - 318 (2009/03/12)
The stereoselective synthesis of (-)-pericosine B, which is the antipode of the cytotoxic metabolite of the fungus Periconia byssoides OUPS-N133 separated from the sea hare, was accomplished in 9 steps in 12% total yield from (-)-quinic acid, together wit
A novel oxidative dimer from protocatechuic esters: Contribution to the total radical scavenging ability of protocatechuic esters
Saito, Shizuka,Kawabata, Jun
, p. 1877 - 1880 (2008/12/22)
A novel oxidative dimer was isolated as a major product from a reaction mixture of methyl protocatechuate and DPPH radical in methanol. Its unusual benzobicyclo[3.2.1]octane structure was elucidated by extensive spectral analysis. This result suggests that the regeneration of catechol structures by the nucleophilic addition of an alcohol molecule on o-quinones and subsequent dimerization is one of the key reactions in the high radical-scavenging activity of protocatechuic esters in an alcoholic solvent.
