462996-04-9

Basic information

• Product Name: DIPHENYL[4-(1H,1H,2H,2H-PERFLUORODECYL)PHENYL]PHOSPHINE
• Synonyms: DIPHENYL[4-(1H,1H,2H,2H-PERFLUORODECYL)PHENYL]PHOSPHINE;[4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-HEPTADECAFLUORODECYL)PHENYL] DIPHENYLPHOSPHINE;[4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecyl)phenyl] diphenylph
• CAS NO: 462996-04-9
• Molecular Formula: C₂₈H₁₈F₁₇P
• Molecular Weight: 708.39
• Mol File: 462996-04-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 81-85 °C
• Boiling Point: 459.7°C at 760 mmHg
• Flash Point: 231.8°C
• Appearance: /
• Vapor Pressure: 3.39E-08mmHg at 25°C
• CAS DataBase Reference: DIPHENYL[4-(1H,1H,2H,2H-PERFLUORODECYL)PHENYL]PHOSPHINE(CAS DataBase Reference)
• NIST Chemistry Reference: DIPHENYL[4-(1H,1H,2H,2H-PERFLUORODECYL)PHENYL]PHOSPHINE(462996-04-9)
• EPA Substance Registry System: DIPHENYL[4-(1H,1H,2H,2H-PERFLUORODECYL)PHENYL]PHOSPHINE(462996-04-9)

Safety Data

• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 462996-04-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C28H18F17P/c29-21(30,22(31,32)23(33,34)24(35,36)25(37,38)26(39,40)27(41,42)28(43,44)45)16-15-17-11-13-20(14-12-17)46(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14H,15-16H2

Upstream product

• 195324-88-0 1-(4'-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecane 
• 1079-66-9 chloro-diphenylphosphine 
• 851869-38-0 Diphenyl-[4-(1H,1H,2H,2H-perfluorodecyl)phenyl]phosphine oxide 

Downstream Products

• 851869-38-0 Diphenyl-[4-(1H,1H,2H,2H-perfluorodecyl)phenyl]phosphine oxide 
• 1211431-44-5 [Ru(η6-p-cymene)Cl2(PPh2(p-C6H4C2H4C8H17))] 
• 1211431-49-0 [Ru(η6-4-phenyl-2-butanol)Cl2(PPh2(p-C6H4C2H4C8H17))] 

Relevant articles and documents

Fluorous Mitsunobu reagents and reactions

A fully fluorous Mitsunobu reaction procedure is introduced. This employs both existing [(C6F13CH2CH2C6H 4)2PPh] and new [C8F17CH2CH2C6H 4PPh2] fluorous phosphines and a new fluorous azodicarboxylate (C6F13CH2CH2OC(O)N=NCOOCH 2CH2C6F13). A procedure involving parallel reactions with representative nucleophiles and alcohols under typical Mitsunobu conditions in THF followed by rapid solid phase extraction (spe) over fluorous silica provides clean products in excellent yields. The fluorous fraction containing the oxidized phosphine oxide and the reduced hydrazide can be readily separated and the starting reagents can be regenerated by appropriate redox reactions in high yield for reuse.