463335-92-4

Upstream product

• 626-05-1 2,6-Dibromopyridine 
• 461451-63-8 5-fluoro-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzonitrile 

Downstream Products

• 752256-68-1 2-{6-[5,8-difluoro-7-(1-methyl-1-triethylsilanyloxyethyl)imidazo[1,2-a]pyridin-3-yl]-pyridin-2-yl}-5-fluorobenzonitrile 

Relevant academic research and scientific papers

5,8-DIFLUOROIMIDAZO[1,2-a]PYRIDINES AS GABA-A α2/α3 LIGANDS FOR TREATING ANXIETY AND/OR DEPRESSION

The present invention provides a compound of formula I: wherein W is a five- or six-membered optionally substituted heteroaromatic ring; or optionally substituted phenyl, substituted meta to the imidazopyridine core by Y-Z where: Y represents a chemical b

8-FLUORIMIDAZO`1,2-A!PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS

A class of 8-fluoroimidazo[1,2-a]pyridine derivatives, substituted at the 3-position by an optionally substituted five-membered or six-membered heteroaromatic ring, being selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 and/or α5 subunit thereof, are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.