46382-84-7 Usage
Type of Compound
Heterocyclic compound
Occurrence
Found in various plants and foods, including tobacco smoke
Potential Carcinogen
Identified as a potential carcinogen due to its ability to induce DNA damage
Mutagenic Properties
Identified as a mutagen due to its ability to interfere with cellular processes
Psychoactive Effects
Reported to have psychoactive effects, potentially contributing to the addictive nature of tobacco smoking
Interaction with Neurotransmitter Receptors
Can interact with neurotransmitter receptors in the brain, leading to altered mood and behavior
Further Research
Further research is needed to fully understand the potential health risks associated with exposure to β-carboline.
Check Digit Verification of cas no
The CAS Registry Mumber 46382-84-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,6,3,8 and 2 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 46382-84:
(7*4)+(6*6)+(5*3)+(4*8)+(3*2)+(2*8)+(1*4)=137
137 % 10 = 7
So 46382-84-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H12N2/c1-8-7-12-13(9(2)14-8)10-5-3-4-6-11(10)15-12/h3-7,15H,1-2H3
46382-84-7Relevant academic research and scientific papers
Synthesis and DNA binding properties of γ-carbolinium derivatives and benzologues
Molina,Vaquero,Garcia-Navio,Alvarez-Builla,De Pascual-Teresa,Gago,Rodrigo,Ballesteros
, p. 5587 - 5599 (2007/10/03)
The 5H-pyrido[4,3-b]indole, 11H-indolo[3,2-c]quinoline, 5H-benzo[f]pyrido[4,3-b]indole, and 13H-benz[5,6]indolo[3,2-c]quinoline heteroaromatic nuclei have been synthesized by the Graebe-Ullmann method by classical heating or under microwave irradiation. These tri-, tetra-, and pentacyclic compounds were transformed into the corresponding cationic derivatives by N-alkylation, and the DNA-binding properties of the resulting cationic systems were examined using UV-vis spectroscopy, viscometric determinations, and molecular modeling techniques. The tetracyclic cations were transformed into bis-salts by means of a diethyl bispiperidine rigid chain and a more flexible polyamide linker, but the low solubility of these bis-salts made the study of their bisintercalating properties difficult.
