463930-77-0

Upstream product

• 102104-08-5 2,4-dimethylpenta-2,3-dienoic acid 
• 100-46-9 benzylamine 
• 201230-82-2 carbon monoxide 

Downstream Products

• 1284293-74-8 (Z)-N-benzyl 3,5,5-trimethyl-4-(3'-methylbuta-1',2'-dienyl)furan-2(5H)-imine 
• 1284293-75-9 (Z)-N-benzyl 4-(3',3'-pentamethylenepropa-1',2'-dienyl)-3,5,5-trimethylfuran-2(5H)-imine 
• 1284293-77-1 (Z)-N-benzyl 3,5,5-trimethyl-4-(3'-methyl-1'-phenylbuta-1',2'-dienyl)furan-2(5H)-imine 
• 1442450-60-3 N-benzyl-2,4-dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pent-3-enamide 
• 1166834-29-2 3-benzyl-6-isopropyl-5-methyl-1,3-oxazine-2,4-dione 
• 1169473-62-4 2,2'-bis(benzylimino)-3,5,5,3',5',5'-hexamethyl-2,5,2',5'-tetrahydro[4,4']bifuranyl 

Relevant academic research and scientific papers

A facile synthesis of β-allenyl furanimines via Pd-catalyzed cyclization of 2,3-allenamides with propargylic carbonates

The Pd(OAc)2/TFP-catalyzed cyclization reaction of 2,3-allenamides in the presence of propargylic carbonates provides an efficient route to β-allenyl furanimine derivatives. Preliminary mechanistic study showed that this reaction was probably initiated by Pd(0) species.

Steric hindrance-controlled Pd(O)-catalyzed coupling-cyclization of 2,3-allenamides and organic iodides. An efficient synthesis of iminolactones and γ-hydroxy-γ-lactams

Under the catalysis of 1 mol % Pd(PPh3)4, the reaction of 4,4-disubstituted 2,3-allenamides and organic iodides in toluene afforded iminolactones stereospecifically in >90% yields using K2CO3 (2 equiv)-5 mol %TBAB as the base. A similar reaction with 4-monosubstituted 2,3-allenamides afforded γ-hydroxy-γ-lactams in relatively lower yields. The N/O-attack selectivity may be determined by the steric effect at the 4-position of 2,3-allenamides.