463936-36-9Relevant academic research and scientific papers
Discovery and SAR of 4-amino-2-biarylbutylurea MCH 1 receptor antagonists through solid-phase parallel synthesis
Guo, Tao,Hunter, Rachael C.,Gu, Huizhong,Rokosz, Laura L.,Stauffer, Tara M.,Hobbs, Doug W.
, p. 3691 - 3695 (2005)
-4-Amino-2-arylbutylbenzamides such as 1 were identified as micromolar MCH 1 receptor (MCH1R) antagonists via screening using a scintillation proximity assay based on [125I]-MCH binding to recombinant, human MCH1R. Subsequent lead optimization
