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1-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-3-yl)-N,N-dimethylmethanamine, also known as GSK189254A, is a chemical compound belonging to the class of methanamines. It has a molecular formula of C14H18N4O and a molecular weight of 258.32 g/mol. 1-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-3-yl)-N,N-dimethylmethanamine is a potent and selective dual orexin receptor antagonist, capable of blocking the signaling of orexin receptors in the brain. Orexin receptors play a role in regulating wakefulness and sleep, so by blocking these receptors, GSK189254A can potentially have sedative and sleep-promoting effects.

46399-68-2

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46399-68-2 Usage

Uses

Used in Pharmaceutical Industry:
1-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-3-yl)-N,N-dimethylmethanamine is used as a therapeutic agent for the treatment of sleep disorders and other neurological conditions related to orexin dysregulation. Its dual orexin receptor antagonist property allows it to potentially promote sleep and reduce wakefulness, making it a promising candidate for addressing sleep-related issues.
Used in Research and Development:
In the field of neuroscience and pharmacology, 1-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-3-yl)-N,N-dimethylmethanamine is used as a research tool to study the role of orexin receptors in sleep-wake cycles and their potential involvement in various neurological conditions. 1-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-3-yl)-N,N-dimethylmethanamine can help researchers better understand the mechanisms behind sleep regulation and develop new treatments for related disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 46399-68-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,6,3,9 and 9 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 46399-68:
(7*4)+(6*6)+(5*3)+(4*9)+(3*9)+(2*6)+(1*8)=162
162 % 10 = 2
So 46399-68-2 is a valid CAS Registry Number.

46399-68-2Downstream Products

46399-68-2Relevant academic research and scientific papers

FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE

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Paragraph 00641, (2016/07/27)

Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.

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