4640-42-0Relevant academic research and scientific papers
Synthesis and antimalarial activity of quinones and structurally-related oxirane derivatives
Carneiro, Paula F.,Pinto, Maria C.R.F.,Marra, Roberta K.F.,Da Silva, Fernando De C.,Resende, Jackson A.L.C.,Rocha E Silva, Luiz F.,Alves, Hilkem G.,Barbosa, Gleyce S.,De Vasconcellos, Marne C.,Lima, Emerson S.,Pohlit, Adrian M.,Ferreira, Vitor F.
, p. 134 - 140 (2015/12/04)
A series of eighteen quinones and structurally-related oxiranes were synthesized and evaluated for in vitro inhibitory activity against the chloroquine-sensitive 3D7 clone of the human malaria parasite Plasmodium falciparum. 2-amino and 2-allyloxynaphthoquinones exhibited important antiplasmodial activity (median inhibitory concentrations (IC50) 10 μM). Oxiranes 6 and 25, prepared respectively by reaction of α-lapachone and tetrachloro-p-quinone with diazomethane in a mixture of ether and ethanol, exhibited the highest antiplasmodial activity and low cytotoxicity against human fibroblasts (MCR-5 cell line). The active compounds could represent a good prototype for an antimalarial lead molecule.
Low hue photobleaches
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, (2008/06/13)
Low hue photobleaching compositions comprising organosilicon(IV) phthalocyanine and naphthalocyanines having Q-band absorption maxima at wavelengths greater than 660 nm and increased triplet state yields whereby production of singlet oxygen is increased.
Low hue photodisinfectants
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, (2008/06/13)
Low hue photo disinfecting compositions comprising organosilicon(IV) phthalocyanine and naphthalocyanines having Q-band absorption maxima at wavelengths greater than 660 nm and increased triplet state yields whereby production of singlet oxygen is increas
Molecular Tapes based on CN...Cl Interactions
Reddy, D. Shekhar,Panneerselvam, Kaliyamoorthy,Pilati, Tullio,Desiraju, Gautam R.
, p. 661 - 662 (2007/10/02)
Weak CN...Cl interactions may be used to design linear molecular tapes.
Octa-alkoxy Phthalocyanine and Naphthalocyanine Derivatives: Dyes with Q-band Absorption in the Far Red or Near Infrared
Cook, Michael J.,Dunn, Adrian J.,Howe, Steven D.,Thomson, Andrew J.,Harrison, Kenneth J.
, p. 2453 - 2458 (2007/10/02)
The lithium alkoxide-catalysed cyclic tetramerisation of various 3,6-dialkoxy-4,5-dichlorophthalonitriles, 1,4-dialkoxynaphthalene-2,3-dicarbonitriles and 3,6-dialkoxyphthalonitriles to give the corresponding metal-free octa-alkoxyoctachlorophthalocyanines, octa-alkoxynaphthalocyanines and octa-alkoxyphthalocyanines is described.An unexpected trans-alkoxylation reaction occurs during the cyclisation of the first two series of precursors.Metal-free phthalocyanines and naphthalocyanines have been converted into derivatives containing various metal ions.Compounds show Q-band absorption in the region 739-862 nm in toluene solution.The fluorescence spectra of selected examples are reported.The solubility of some of the compounds has been measured in a formulation of liquid crystal materials.
