4640-44-2 Usage
Uses
Used in Pharmaceutical Industry:
3-aminocyclobutanol (SALTDATA: FREE) is used as a building block for the preparation of various pharmaceuticals and bioactive molecules. Its unique chemical properties allow it to be a key component in the synthesis of a wide range of compounds with therapeutic potential.
Used in Organic Synthesis:
3-aminocyclobutanol (SALTDATA: FREE) is used as a versatile intermediate in organic synthesis, enabling the production of a broad range of compounds. Its chemical properties make it a valuable asset in the development of new chemical entities and the improvement of existing ones.
Used in Academic Research and Development:
3-aminocyclobutanol (SALTDATA: FREE) is utilized in academic research and development within the field of organic chemistry. Its unique structure and properties make it an interesting subject for study, potentially leading to new insights and advancements in chemical synthesis and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4640-44-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,4 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4640-44:
(6*4)+(5*6)+(4*4)+(3*0)+(2*4)+(1*4)=82
82 % 10 = 2
So 4640-44-2 is a valid CAS Registry Number.
4640-44-2Relevant academic research and scientific papers
Potent and cellularly active 4-aminoimidazole inhibitors of cyclin-dependent kinase 5/p25 for the treatment of Alzheimer's disease
Helal, Christopher J.,Kang, Zhijun,Lucas, John C.,Gant, Thomas,Ahlijanian, Michael K.,Schachter, Joel B.,Richter, Karl E.G.,Cook, James M.,Menniti, Frank S.,Kelly, Kristin,Mente, Scot,Pandit, Jay,Hosea, Natalie
supporting information; experimental part, p. 5703 - 5707 (2010/04/30)
Utilizing structure-based drug design, a 4-aminoimidazole heterocyclic core was synthesized as a replacement for a 2-aminothiazole due to potential metabolically mediated toxicity. The synthetic route utilized allowed for ready synthesis of 1-substituted-4-aminoimidazoles. SAR exploration resulted in the identification of a novel cis-substituted cyclobutyl group that gave improved enzyme and cellular potency against cdk5/p25 with up to 30-fold selectivity over cdk2/cyclin E.
