464200-92-8

Upstream product

• 50562-79-3 1-(4-tolylsulfonyl)indole-3-carboxaldehyde 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 487-89-8 Indole-3-carboxaldehyde 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 760968-16-9 methyl 2-benzyloxycarbonylamino-3-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-3-hydroxypropionate 
• 760968-09-0 methyl 2,3-dihydroxy-3-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-propionate 
• 634599-51-2 (E)-3-(1-tosyl-1H-indol-3-yl)prop-2-en-1-ol 
• 863976-55-0 (2R,3S)-3-Hydroxy-2-(4-nitro-benzenesulfonyloxy)-3-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-propionic acid methyl ester 
• 760967-93-9 2-benzyloxycarbonylamino-3-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-3-triisopropylsilanyloxypropionic acid 
• 760968-17-0 (2S,3R)-2-Benzyloxycarbonylamino-3-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-3-triisopropylsilanyloxy-propionic acid methyl ester 
• 760967-91-7 2-benzyloxycarbonylamino-3-(tert-butyldimethylsilanyloxy)-3-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-propionic acid 
• 760968-15-8 2-benzyloxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-3-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-propionic acid methyl ester 
• 760968-14-7 methyl 2-azido-3-(tert-butyldimethylsilanyloxy)-3-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-propionate 
• 760968-12-5 (2S,3S)-2-Azido-3-hydroxy-3-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-propionic acid methyl ester 

Relevant academic research and scientific papers

Diastereoselective Synthesis of trans-2,3-Diaryl(heteroaryl)-3,6-dihydropyrans by an Allylboration/Ring-Closing-Metathesis Sequence

trans-2,3-Diaryl(heteroaryl)-dihydropyrans were synthesized by an allylboration/ring-closing-metathesis sequence, using allylboranes formed in situ from the corresponding allylic alcohols. Aryl(heteroaryl) substituents were thus installed diastereoselectively onto dihydropyran rings in a trans fashion. These disubstituted dihydropyrans were further transformed into monosaccharide-like tetrahydropyrans.

Synthesis and serotonin receptor affinities of a series of trans-2- (indol-3-yl)cyclopropylamine derivatives

A series of four racemic ring-substituted trans-2-(indol-3- yl)cyclopropylamine derivatives was synthesized and tested for affinity at the 5-HT(1A) receptor, by competition with [3H]-8-OH-DPAT in rat hippocampal homogenates, and for affinity at