4644-03-5

Basic information

• Product Name: 1,4-dihydroxy-2-(morpholin-4-yl)anthracene-9,10-dione
• Synonyms: 1,4-Dihydroxy-2-(morpholin-4-yl)-9,10-anthraquinone; 9,10-Anthracenedione, 1,4-dihydroxy-2-(4-morpholinyl)-
• CAS NO: 4644-03-5
• Molecular Formula: C₁₈H₁₅NO₅
• Molecular Weight: 325.3154
• Mol File: 4644-03-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 622.6°C at 760 mmHg
• Flash Point: 330.3°C
• Density: 1.483g/cm³
• Vapor Pressure: 4.31E-16mmHg at 25°C
• Refractive Index: 1.694
• CAS DataBase Reference: 1,4-dihydroxy-2-(morpholin-4-yl)anthracene-9,10-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-dihydroxy-2-(morpholin-4-yl)anthracene-9,10-dione(4644-03-5)
• EPA Substance Registry System: 1,4-dihydroxy-2-(morpholin-4-yl)anthracene-9,10-dione(4644-03-5)

Safety Data

• Hazardous Substances Data: 4644-03-5(Hazardous Substances Data)

Usage

Type

Synthetic anthracenedione derivative

Antineoplastic

It has the ability to inhibit the growth of cancer cells.

Immunosuppressive

It can suppress the immune system, reducing inflammation.

Mechanism of Action

Intercalates DNA and interferes with the synthesis of nucleic acids.

Acute myeloid leukemia

A type of blood cancer.

Non-Hodgkin's lymphoma

A type of cancer that begins in the lymphatic system.

Prostate cancer

Cancer that occurs in the prostate gland.

Multiple sclerosis

A disease that affects the central nervous system.

Bone marrow suppression

Can lead to a decrease in the production of blood cells.

Cardiotoxicity

Can cause damage to the heart muscle.

Precautions

Its use is carefully monitored and reserved for patients who have not responded to other treatments.

Upstream product

• 110-91-8 morpholine 
• 81-64-1 1,4-dihydroxy-9,10-anthracenedione 

Relevant articles and documents

Acetylation of 2-(1-piperazinyl)- and 2-morpholino-1,4-dihydroxyanthraquinones

Successive acetylation of 2-(1-pipepazinyl)- and 2-morpholino-1,4-dihydroxyanthraquinones with acetic anhydride was accomplished.