465514-39-0

Basic information

• Product Name: 1-[4-(TRIFLUOROMETHYL)-2-PYRIMIDINYL]-4-PIPERIDINECARBOXYLIC ACID
• Synonyms: ART-CHEM-BB B023453;BUTTPARK 31\08-79;AKOS B023453;1-[4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]PIPERIDINE-4-CARBOXYLIC ACID;1-[4-(TRIFLUOROMETHYL)PYRIMID-2-YL]PIPERIDINE-4-CARBOXYLIC ACID;1-[4-(TRIFLUOROMETHYL)-2-PYRIMIDINYL]-4-PIPERIDINECARBOXYLIC ACID;1-[4-(Trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxylicacid97%;1-[4-(TRIFLUOROMETHYL)-PYRIMIDIN-2-YL]-4-PIPERIDINECARBOXYLIC ACID
• CAS NO: 465514-39-0
• Molecular Formula: C₁₁H₁₂F₃N₃O₂
• Molecular Weight: 275.23
• Product Categories: Carboxylic Acids;Pyrans, Piperidines &Piperazines;Carboxylic Acids;Pyrans, Piperidines & Piperazines
• Mol File: 465514-39-0.mol

Chemical Properties

• Melting Point: 140 °C
• Boiling Point: 430.2°C at 760 mmHg
• Flash Point: 214°C
• Appearance: /
• Density: 1.419g/cm³
• Vapor Pressure: 3.63E-08mmHg at 25°C
• Refractive Index: 1.513
• CAS DataBase Reference: 1-[4-(TRIFLUOROMETHYL)-2-PYRIMIDINYL]-4-PIPERIDINECARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(TRIFLUOROMETHYL)-2-PYRIMIDINYL]-4-PIPERIDINECARBOXYLIC ACID(465514-39-0)
• EPA Substance Registry System: 1-[4-(TRIFLUOROMETHYL)-2-PYRIMIDINYL]-4-PIPERIDINECARBOXYLIC ACID(465514-39-0)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 465514-39-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-[4-(TRIFLUOROMETHYL)-2-PYRIMIDINYL]-4-PIPERIDINECARBOXYLIC ACID is used as a potential pharmaceutical agent for its possible biological activities and structural characteristics that may contribute to the development of new drugs or therapeutic agents. Its specific application reason is yet to be determined based on further research and clinical trials, but its unique structure suggests it may have roles in various medicinal applications.

InChI:InChI=1/C11H12F3N3O2/c12-11(13,14)8-1-4-15-10(16-8)17-5-2-7(3-6-17)9(18)19/h1,4,7H,2-3,5-6H2,(H,18,19)

Relevant articles and documents

1, 4-DISUBSTITUTED PIPERIDINES AS VASOPRESSIN RECEPTOR VIA ANTAGONISTS

The present invention provides compounds of formula (1) compositions comprising such compounds; the use of such compounds in therapy (such as in the treatment of dysmenorrhoea); and methods of treating patients with such compounds; wherein A and G are as defined herein.

TETRAHYDRO-NAPHTHALENE AND UREA DERIVATIVES

This invention relates to a hydroxy-tetrahydro-naphthalene or an urea derivative formula (I) and salts thereof which are useful as active ingredients of pharmaceutical preparations, wherein A represents formula (II) or (III) wherein # represents the connection position to the molecule and Q1a, Q2a, Q3a and Q4a are defined, and E represents formula (IV) or (V) wherein # represents the connection position to the molecule and Q1b, Q2b, Q3b, Q4b, Q5b, R1b, na, ma, Xa and Ra are defined.

PIPERIDINE/CYCLOHEXANE CARBOXAMIDE DERIVATIVES FOR USE AS VANILLOID RECEPTOR MODULATORS

Certain compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, P, P', X, m and n are as defined in the specification, a process for preparing such compounds, a pharmaceutical composition c