4658-46-2Relevant academic research and scientific papers
REACTION OF OXIRANES WITH DIANIONS OF SECONDARY AMINES. NEW ENTRY TO 5-ALKYLSUBSTITUTED γ-LACTAMS
Takahata, Hiroki,Wang, Eng-Chi,Yamazaki, Takao
, p. 1159 - 1166 (2007/10/02)
The oxirane ring cleavage with dilithiated secondary amides was accelerated by the addition of boron trifluoride-etherate to afford γ-hydroxyamides, which were transformed into 5-alkylsubstituted γ-lactams via an intramolecular N-alkylation reaction.
